They use Ohmline!
Oncology & Immunology
Dr. María Linares and Dr. María Hernández are working with Ohmline to generate new treatments in different hematological tumors, with a special focus on multiple myeloma. They have already obtained promising preliminary results with Ohmline-based combination therapies which specifically target malignant cells, without compromising non-pathogenic T cells.
Dr. Alberto Díaz-Ruiz is working with Ohmline to reposition non-oncologic therapies to treat glioblastoma tumors in the context of a collaborative Industrial PhD program between IMDEA Nutrition and Lifesome Therapeutics S.L., funded by the Community of Madrid (IND2024/BMD-33979). In this context, the project has already identified a synergistic antitumoral effect between Ohmline and an antifungal compound. Next steps include the cellular and molecular characterization of this effect and the validation in complex models.
Microbiology
Biophysics
Through a strategic partnering with the Portuguese company Bac3Gel, we are using Ohmline to encapsulate well-established antibiotics, overcoming resistance to them in the context of airborne bacterial infections. Ohmline-based combination therapies are tested in Bac3Gel’s innovative 3D culture systems, which optimally resemble the airway mucosa. This project is funded by CDTI (MultiPaís 2024 program).
Thank you to all our partners who help us with the biophysical characterization of Ohmline nanoparticles!
- Dr. Paul-Alain Jaffres (Université de Bretagne Occidentale)